TY - JOUR AU - Dincoglan, Ferrat AU - Sager, Omer AU - Demiral, Seluck AU - Beyzadeoglu, Murat PY - 2019/02/18 Y2 - 2024/03/28 TI - Multimodality Imaging for Radiosurgical Management of Arteriovenous Malformations JF - Asian Journal of Pharmacy, Nursing and Medical Sciences JA - AJPNMS VL - 7 IS - 1 SE - Articles DO - 10.24203/ajpnms.v7i1.5661 UR - https://www.ajouronline.com/index.php/AJPNMS/article/view/5661 SP - AB - <p><strong>Background:</strong> Cerebral arteriovenous malformations (AVMs) are rarely seen congenital vascular anomalies. AVMs may lead to intracranial hemorrages due to disorganized tangle of vessels. Lifetime risk of bleeding from AVMs may be significant given the diagnosis at typically earlier ages of the lifespan, and complications associated with hemorrhage may lead to substantial morbidity or mortality. Management of AVMs aims at eliminating or reducing the risk of subsequent bleeding. In this context, microvascular surgical resection, endovascular embolization and radiosurgical treatment may be used for management of AVMs.</p><p><strong>Objective:</strong> In this study, we assessed the incorporation of Magnetic Resonance Imaging (MRI) in treatment planning for AVM radiosurgery. </p><p><strong>Methods:</strong> We identified 25 patients receiving radiosurgery for AVMs at our institution. Radiosurgery target volumes generated by using CT-only based imaging and CT-MR fusion based imaging for each patient were evaluated.</p><p><strong>Results:</strong> Twenty five patients undergoing SRS for AVMs were evaluated for target volume determination in this study. Mean target volume was 4.9 cc (range: 1.3-15.9 cc) on CT-only imaging, 5.7 cc (range: 1.4-16.7 cc) on CT-MR fusion based imaging, and 5.9 cc (range: 1.4-16.9 cc) on consensus decision of all treating physicians with colleague peer review. Target definition based on CT-MR fusion based imaging was identical to the consensus decision of all treating physicians in majority of patients.</p><p><strong>Conclusions:</strong> Treatment planning for AVM radiosurgery may be improved by incorporating CT-MR fusion based imaging, which clearly should be supplemented with additional data from angiography. There is need for additional studies to establish a consensus on optimal target definition by multimodality imaging for SRS of AVMs.</p> ER -