Prevalence of Metabolic Syndrome among Students of Faculty of Health Science and Technology in Ebonyi State University,

Authors

  • Kingsley K. Anya
  • Godwin O. Okoro
  • Charles C. Onyenekwe
  • Samuel Ayobami Fasogbon Public Health In-Vitro Diagnostics Control Laboratory, Medical Laboratory Science Council of Nigeria
  • Ahmed O. Adebayo

DOI:

https://doi.org/10.24203/ajas.v7i6.6000

Keywords:

Prevalence, Metabolic Syndrome, Blood pressure, Obesity

Abstract

Metabolic impairments could be seen at any point in human development. Although emphasis has been placed on older adults but it could be encountered in any age brackets. The aim of this study was to compare prevalence rates using different definitions of Metabolic syndrome (MetS) among students of Faculty of Health Sciences and Technology (FHST) in Ebonyi State University (EBSU), Abakaliki.  This was a cross-sectional study involving 80 students (28 male students and 52 female students) recruited from among students of FHST in EBSU, Abakaliki, Ebonyi State, Nigeria. MetS was defined in three different ways [by International Diabetes Federation (IDF), National Cholesterol Education Program—Adult Treatment Panel III (NCEP-ATPIII), or World Health Organization (WHO) criteria]. Prevalence was found to be 6.3%, 2.5% and 7.5% using NCEP-ATP III, WHO, and IDF definitions respectively.  The most common MetS components among female students using the NCEP-ATP III criteria were high blood pressure (5.8%) and abdominal obesity (5.8%), whilst low HDL-C concentrations, high blood pressure and abdominal obesity were most common among male students (7.1 % for each component mentioned). According to WHO, abdominal obesity (7.1%) and hyperglycaemia (7.1%) were the most common MetS components among male students. The most common MetS components among participants using the IDF criteria were abdominal obesity and high blood pressure. While some participants did not meet the MetS criteria of the NCEP-ATP III, WHO and IDF criteria (50%), many had one (30%) or two (13.8%) components and may be at risk of developing the syndrome in the future. The mean values of the risk factors  used as criteria for the diagnosis of MetS were relatively normal in the study population thereby masking the presence of MetS, thus showing that the prevalence of MetS may gradually increase undetected unless individual members of the study population are subjected to laboratory investigation using different criteria for diagnosis of MetS. Therefore, traditional risk factors might be late markers for diagnosis of MetS since findings from this study showed that MetS was only detected in participants that already had it.

References

Alberti, K.G., Eckel, R.H., and Grundy, S.M. (2009). Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force onEpidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association;World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation,120:1640-1645.

Alberti, K.G., Zimmet, P., and Shaw, J. (2006). Metabolic syndrome-a new world-wide definition.A consensus statement from the International Diabetes Federation. DiabetesMedicine,23:469-480.

Tokin A. (2004). The metabolic syndrome: A growing problem. European Heart Journal, Supplement 6: A32-A42.

Meigs, J.B., Larson, M.G., and D’ Agostino, R.B. (2002). Coronary artery calcification in type 2 diabetes and insulin resistance. The Famingham Offspring Study. Diabetes Care,25:1313-1319.

Ford, E.S., Giles, W.H., and Dietz, W.H. (2002). Prevalence of the metabolic syndrome among US adults: Findings from the Third National Health and Nutrition Examination. Survey.Journal of American Medical Association, 287:356-359.

Ford, E.S., Li, C., and Sattar, N. (2008). Metabolic syndrome and incident diabetes: current state of the evidence. Diabetes Care,31:1898-1904.

Miranda, P.J., Defronzo, R.A., Califf, R.M., and Guyton, J.R. (2005). Metabolic syndrome: definition, pathophysiology and mechanisms. American Heart Journal,149: 33- 45.

Fezeu, L., Balkau, B., Kengne, A.P., Sobngwi, E., and Mbanya, J.C. (2007). Metabolic syndromein a sub-Saharan African setting: central obesity may be the key determinant. Atherosclerosis,193:70-76.

Al-Nozha, M., Al-Khadra, A., Arafah, M.R., Al-Maatouq, M.A., Khalil, M.Z., and Khan, N.B. (2005). Metabolic syndrome in Saudi Arabia. Saudi Medical Journal, 26:1918-1925.

Pemminati, S., Prabha, A.M.R., Pathak, R., and Pai, M.R. (2010). Prevalence of metabolic syndrome (MetS) using IDF 2005 guidelines in a semi urban south Indian (Boloor Diabetes Study) population of Mangalore. Journal of Associate Physicians India, 58:674-677.

Tran, A., Gelaye, B., Girma, B., Lemma, S., Berhane, Y., and Bekele, T. (2011). Prevalence of metabolic syndrome among working adults in Ethiopia. International Journal of Hypertension.

Gyakobo, M., Amoah, A.G.B., Martey-Marbell, D., and Snow, R.C. (2012). Prevalence of the metabolic syndrome in a rural population in Ghana. BMC Endocrine Disorders, 12:25.

Ulasi, I.I., Ijoma, C.K., and Onodugo, O.D. (2010). A community-based study of hypertension and car diometabolic syndrome in semi-urban and rural communities in Nigeria. BMC Health ServiceResources10:71.

Adediran, O., Akintunde, A.A., Edo, A.E., Opadijo, O.G., and Araoye, A.M. (2012). Impact of urbanization and gender on frequency of metabolic syndrome among native Abuja settlers in Nigeria. Journal of Cardiovascular Disease Resources, 3:191-196.

Alebiosu, Co., and Odusan, B.O. (2004). Metabolic Syndrome in subjects with type 2 diabetes mellitus. Journal of National Medical Association, 96:817–821.

Isezuo, S.A. (2005a). Is high density lipoprotein cholesterol useful in diagnosis of metabolic syndrome in native Africans with type 2 diabetes? Ethnic Disorders, 15:6-10.

Reaven, G.M. (1988). Banting lecture: Role of insulin resistance in human disease. Diabetes, 37:1595-1607.

Marchesini, G., Melchionda, N., Apolone, G., Cuzzolaro, M., Mannucci, E., and Grossi, E.(2004).The metabolic syndrome in treatment seeking obese persons. Metabolism, 53:435-440.

Ismail, M.F. (2012). Metabolic syndrome among obese Qataris attending primary health care centers in Doha. 2010. Journal of Family and CommunityMedicine,19:7-11.

Surana, S.P., Shah, D.B., Gala, K., Hoskote, S.S., Gill, N., and Joshi, A.R. (2008). Prevalence of metabolic syndrome in an Indian population using the NCEP ATP III. Journal of Association of Physicians India,56:865-868.

Akintunde, A.A., Ayodele, O.E., Akinwusi, P.O., and Opadijo, G.O. (2011). Metabolic syndrome: Comparison of occurrence using three definitions in hypertensive patients. Clinical Medicine Resources, 9:26-31.

Termizy, H.M., and Matauzy, M. (2009). Metabolic syndrome and its characteristics among obese patients attending an obesity clinic. Singapore Medical Journal 50: 390-394.

Mottillo, S., Filion, K.B., Genest, J., Joseph, L., Pilote, L., Poirier, P., Rinfret, S.,and Schiffrin, E.L., and Eisenberg, M.J. (2010). The metabolic syndrome and cardiovascular risk a systematic review and meta-analysis. Journal of American College of Cardiology,56:1113-1132.

Hanson, R.L., Imperatore, G., Bennett, P.H., and Knowler, W.C. (2002). Components of the metabolic syndrome" and incidence of type 2 diabetes. Diabetes, 51:3120-3127.

World Health Organization [WHO]. (2008). Prevention of chronic disease: A vital investment. Geneva, Switzerland: Author.

Alberti, K.G., and Zimmet, P.Z. (1998). Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabetic Medicine, 15:539-553.

Alberti, K.G., Zimmet, P.Z., and Shaw, J. (2005). The metabolic syndrome-a new worldwide definition. Lancet,366:1059-1062.

Chobanian, A.V., Bakris, G.L., and Black H.R. (2003). Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension, 42(6):1206–1252

George, A., Paul, Z.M., and Jonath, S. (2006.) The International Diabetes Federation consensus worldwide definition of metabolic syndrome. International Diabetes Federation

Oguoma, V.M., Nwose, E.U., and Richards, R.S. (2015). Prevalence of cardio-metabolic syndrome in Nigeria: A systematic review. Public Health, 129:413-423.

Iloh, G.P., Ikwudinma, A.O., and Obiegbu, N.P. (2013). Obesity and its cardio-metabolic co-morbidities among adult Nigerians in a primary care clinic of a tertiary hospital in South-Eastern Nigeria. Journal of Family Medicine and Primary Care,2:20-26

Alshehri, A.M. Metabolic syndrome and cardiovascular risk. (2010). Journal of Family Community Medicine, 17:73-8

Motala, A.A., Mbanya, J.C., and Ramaiya, K.L. (2009). Metabolic syndrome in sub-Saharan Africa. Ethnicity & disease, 19(2):S2–S8.

Kelliny, C., William, J., Riesen, W., Paccaud, F., and Bovet, P. (2008). Metabolic syndrome according to different definitions in a rapidly developing country of the African region. CardiovascularDiabetology, 7(27).

28.Njelekela, M. A., Mpembeni, R., and Muhihi, A. (2009). Genderrelated differences in the prevalence of cardiovascular disease risk factors and their correlates in urban Tanzania. BMC Cardiovascular Disorders, 9(30).

Adegoke, O. A., Adedoyin, R. A., Balogun, M. O., Adebayo, R. A., Bisiriyu, L. A., and Salawu, A. A. (2010). Prevalence of metabolic syndrome in a rural community in Nigeria Metabolic Syndrome and Related Disorders, 8(1):59–62.

Zhang, J., Pronyuk, K.H., Kuliesh, O.V., and Chenghe, S. (2015). Adiponectin, Resistin and Leptin: Possible Markers of Metabolic Syndrome. Endocrinology and metabolic syndrome, 4:212.

Conti, E., Carrozza, C., Capoluongo, E. (2004). Insulin-like growth factor-1 as a vascular protective factor. Circulation, 110(15):2260–2265.

Deen, D. (2004). Metabolic syndrome: time for action. American Family Physician. 69:2875–2882.

Santos, A. C., and Barros, H. (2007). Impact of metabolic syndrome definitions on prevalence estimates: a study in a Portuguese community.Diabetes and Vascular Disease Research,4(4):320–327.

Can, A. S., and Bersot, T. P. (2007). Analysis of agreement among definitions of metabolic syndrome in nondiabetic Turkish adults: a methodological study.BMC Public Health, 7(353)

Oladapo, O. O., Salako, L., Sodiq, O., Shoyinka, K., Adedapo, K., and Falase, A. O. (2010). A prevalence of cardiometabolic risk factors among a rural Yoruba south-western Nigerian population: a population-based survey.Cardiovascular Journal of Africa, 21(1):31.

Sodjinou, R., Agueh, V., Fayomi, B., and Delisle, H. (2008). Obesity and cardio-metabolic risk factors in urban adults of Benin: relationship with socio-economic status, urbanisation, and lifestylepatterns. BMC Public Health,8(84).

Onyegbutulem, H. C., H-Onyegbutulem, P. I., Reimann, M., Li, J., Bornstein, S. R., and Schwarz, P. E. (2009). Metabolic syndrome in Africa: an emerging perspective. Hormone and Metabolic Research, 41(2)75–78.

Murray, C. J. L., and Lopez, A. D. (1997). Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. Lancet, 349 (9064):1498–1504.

Mathers, C.D., and Loncar, D. (2006). “Projections of global mortality and burden of disease from 2002 to 2030.†PLoS Medicine, 3(11): article e442.

Downloads

Published

2019-12-25

How to Cite

Anya, K. K., Okoro, G. O., Onyenekwe, C. C., Fasogbon, S. A., & Adebayo, A. O. (2019). Prevalence of Metabolic Syndrome among Students of Faculty of Health Science and Technology in Ebonyi State University,. Asian Journal of Applied Sciences, 7(6). https://doi.org/10.24203/ajas.v7i6.6000