Evaluation of the Relaxation Times for Rhizophora spp. Wood as Human Tissue Equivalent for MRI Breast Phantom


  • Baker Ababneh Universiti Sains Malaysia
  • Abd Aziz Tajuddin Universiti Sains Malaysia
  • Rokiah Hashim Universiti Sains Malaysia
  • Ibrahim Lutfi Shuaib Universiti Sains Malaysia
  • Suzana Mat Isa Universiti Sains Malaysia
  • Amer AL-Jarrah Universiti Sains Malaysia


magnetic resonance imaging(MRI). Phantom. Relaxation times T1, T2. Rhizophora spp.


Rhizophora spp. type of mangroves have been tested to make it as a possible human breast tissue equivalent magnetic resonance image (MRI) phantom that is realistic, inexpensive and stable over time. This study involves variations of relaxation times with water distribution inside Rhizophora spp. wood phantom. The sample was fabricated to comparable breast phantom dimension and evaluated by using breast coils at different MRI imaging sequences available for diagnosis using 1.5T clinical MRI equipment. The T1 relaxation time were measured using spin echo sequence with six repetitions and fast spin echo sequence were used to measure T2 relaxation time with six echoes. The fabricated phantom was found to have mean T1 values of ROI 1, ROI 2, ROI 3 and ROI 4, 434.78 ms ± 23.05 , 714.28ms ± 16, 666.67ms ± 19.70ms and 454.55ms ± 26.63, respectively. T2 values of 76.92 ± 20.85ms, 84.03ms ± 29.29, 89.28ms ± 29.07 and 79.36ms ±19.2, respectively. The change on the results due to water distribution and organic substances inside the sample. The relaxation times measured are similar to human breast tissue, especially fat and normal fibroglandular tissue.

Author Biographies

Baker Ababneh, Universiti Sains Malaysia

School of Physics

Abd Aziz Tajuddin, Universiti Sains Malaysia

Advanced Medical and Dental Institute (AMDI)

Rokiah Hashim, Universiti Sains Malaysia

School of Industrial Technology

Ibrahim Lutfi Shuaib, Universiti Sains Malaysia

Advanced Medical and Dental Institute (AMDI)

Suzana Mat Isa, Universiti Sains Malaysia

Advanced Medical and Dental Institute (AMDI)

Amer AL-Jarrah, Universiti Sains Malaysia

School of Physics


Nyu LG, Udupa JK. On standardizing the MR image intensity scale. image. 1999;1081.

Schnack HG, van Haren NE, Pol H, Hilleke E, Picchioni M, Weisbrod M, et al. Reliability of brain volumes from multicenter MRI acquisition: a calibration study. Human brain mapping. 2004;22:312-20.

Ohno S, Kato H, Harimoto T, Ikemoto Y, Yoshitomi K, Kadohisa S, et al. Production of a human-tissue-equivalent MRI phantom: optimization of material heating. Magnetic resonance in medical sciences: MRMS: an official journal of Japan Society of Magnetic Resonance in Medicine. 2007;7:131-40.

Hellerbach A, Schuster V, Jansen A, Sommer J. MRI Phantoms–Are There Alternatives to Agar? PloS one. 2013;8:e70343.

Liney GP, Tozer DJ, Turnbull LW. A Simple and Realistic Tissueâ€Equivalent Breast Phantom for MRI. Journal of Magnetic Resonance Imaging. 1999;10:968-71.

Müller U, Bammer R, Halmschlager E, Stollberger R, Wimmer R. Detection of fungal wood decay using magnetic resonance imaging. European Journal of Wood and Wood Products. 2001;59:190-4.

Damadian R. Tumor detection by nuclear magnetic resonance. Science. 1971;171:1151-3.

Flibotte S, Menon R, MacKay A, Hailey JR. Proton magnetic resonance of western red cedar. Wood and fiber science. 1990;22:362-76.

Hall LD, Rajanayagam V, Stewart WA, Steiner PR. Magnetic resonance imaging of wood. Canadian journal of forest research. 1986;16:423-6.

Wang PC, Chang SJ. Nuclear magnetic resonance imaging of wood. Wood and fiber science. 1986;18:308-14.

Araujo C, MacKay A, Hailey J, Whittall K, Le H. Proton magnetic resonance techniques for characterization of water in wood: application to white spruce. Wood Science and Technology. 1992;26:101-13.

Hall LD, Rajanayagam V, Stewart WA, Steiner PR, Chow S. Detection of hiddon morphology of wood by magnetic resonance imaging. Canadian Journal of Forest Research. 1986;16:684-7.

Peter H. The Biology of mangroves. Oxford University Press; 1999.

Adolphe A, Ndongo D, Simon L, Nico K, Farid D-G. Commercial activities and subsistence utilization of mangrove forests around the Wouri estuary and the Douala-Edea reserve (Cameroon). 2009.

Bradley D, Tajuddin A, Sudin CWACW, Bauk S. Photon attenuation studies on tropical hardwoods. International Journal of Radiation Applications and Instrumentation Part A Applied Radiation and Isotopes. 1991;42:771-3.

Sudin C. Kayu tropika sebagai bahantara setaraan tisu untuk kajian dosimetri. Universiti Sains Malaysia, Penang, Malaysia. 1993.

Tajuddin A, Sudin CCW, Bradley D. Radiographic and scattering investigation on the suitability of Rhizophora sp. as tissue-equivalent medium for dosimetric study. Radiation Physics and Chemistry. 1996;47:739-40.

Mamani JB, Pavon LF, Miyaki LAM, Sibov TT, Rossan F, Silveira PH, et al. Intracellular labeling and quantification process by magnetic resonance imaging using iron oxide magnetic nanoparticles in rat C6 glioma cell line. Einstein (Sao Paulo). 2012;10:216-21.

Gold GE, Han E, Stainsby J, Wright G, Brittain J, Beaulieu C. Musculoskeletal MRI at 3.0 T: relaxation times and image contrast. American Journal of Roentgenology. 2004;183:343-51.

Fromm JH, Sautter I, Matthies D, Kremer J, Schumacher P, Ganter C. Xylem water content and wood density in spruce and oak trees detected by high-resolution computed tomography. Plant Physiology. 2001;127:416-25.

Sadegh AN. Variation of Basic Density in Eucalyptus camaldulensis dehnh wood grown in Iran. Middle-East Journal of Scientific Research. 2012;11:1472-4.

Dean KI, Majurin M-L, Komu M. Relaxation times of normal breast tissues: changes with age and variations during the menstrual cycle. Acta Radiologica. 1994;35:258-61.

Carneiro A, Vilela G, de Araujo D, Baffa O. MRI relaxometry: methods and applications. Brazilian journal of physics. 2006;36:9-15.

Hendrick RE. Breast MRI: fundamentals and technical aspects: Springer Science & Business Media; 2007.



How to Cite

Ababneh, B., Tajuddin, A. A., Hashim, R., Shuaib, I. L., Isa, S. M., & AL-Jarrah, A. (2015). Evaluation of the Relaxation Times for Rhizophora spp. Wood as Human Tissue Equivalent for MRI Breast Phantom. Asian Journal of Applied Sciences, 3(6). Retrieved from https://www.ajouronline.com/index.php/AJAS/article/view/3323

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