In Vitro Susceptibility Test of Ciprofloxacin on Different Clinical Isolates
Ciprofloxacin is a quinolone indicated for the treatment of gram positive and gram negative bacterial infections in animals. The study was aimed at evaluating the susceptibility pattern of six different bacteria isolates. The bacteria isolates were Staphylococcus spp., E coli, Pseudomonas spp, Klebsiella spp, Salmonella pullorum and Salmonella gallinarum. The bacteria used for the study were isolated from different animals including chicken. 10% of the total livestock in the farm was used as sample size. The study was skewed towards veterinary science because of the relevance of livestock in the study area. Disc diffusion method was employed and the interpretation of the result was in line with National committee of clinical Laboratory standards. (NCCLS).The rational for using 5 brands of ciprofloxacin was based on the complaint by many farmers on the performance level of some ciprofloxacin at the expense of others. The brands of ciprofloxacin designated as A, B, C, D, and E was obtained from Ariaria International market Aba, Abia State Nigeria. The result of the study showed that brand A and D had 100% effectively, while brand E had 60% affectivity. Staphylococcus spp was 100% susceptible to all the brands of ciprofloxacin followed by E. coli 96.4%, Pseudomanas spp 93.6%. klebsiella spp 90.2%, Salmonella pullorum and Salmonella gallinarum had 88.4% susceptibility for ciprofloxacin. The study showed that there was a significance difference (P<0.05) between brand A compare to all other brands.
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